The central role of clock genes in orchestrating diverse timing behaviors in Drosophila: An integrative genetic and molecular review

Core clock genes in Drosophila are involved in multiple biological timing processes, including sleep and reproductive timing.

• Clock genes like period, timeless, Clock, and cycle are linked to circadian rhythms and various timing-related behaviors.
• These genes contribute to processes such as sleep regulation, developmental timing, and metabolic homeostasis.
• Clock-gene functions are influenced by factors like cellular context, environmental inputs, and regulatory mechanisms.
• The review suggests that biological timing phenomena may be understood through the modular reuse of conserved molecular components.

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