Frontiers in cell and developmental biologyAug 1, 2026

CNOT11 loss is linked to self-cleaning cell processes and inflammation signaling in cancer cells

Longevity & Aging Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Aug 3, 2026

Abstract

The CCR4-NOT complex is a key regulator of mRNA decay.

CNOT11 is a subunit of the CCR4-NOT complex that is specific to vertebrates.
The function of CNOT11 in mRNA decay processes is not well understood.
Understanding CNOT11's role could provide insights into the regulation of gene expression.

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