Conversions of Roux-en-Y gastric bypass to duodenal switch (SADI-S and BPD-DS) for weight regain

Oct 23, 2019Surgical endoscopy

Using duodenal switch surgeries (SADI-S and BPD-DS) to treat weight regain after Roux-en-Y gastric bypass

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Abstract

The mean percentage of total weight loss after conversion to duodenal switch was 26.4% at 18 months.

Conversions from Roux-en-Y gastric bypass to duodenal switch can lead to significant additional weight loss.
Weight loss was measured at various intervals, showing 18.4% at 6 months and 25.7% at 24 months.
The rate of decrease in body mass index was slower for patients who underwent single anastomosis duodeno-ileal bypass compared to those who had biliopancreatic diversion.
Complications such as duodenal stump leaks and malnutrition were observed following the conversions.
No mortality was reported among the patients in the study.

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BACKGROUND: Duodenal switch is a choice of conversion when patients fail to lose or regain weight after Roux-en-Y gastric bypass (RYGB). This study aims to evaluate the effectiveness and safety of duodenal switch as a secondary operation for patients who presented with insufficient weight loss or weight regain after a RYGB.

METHODS: A retrospective chart review was performed on 15 patients who underwent a conversion of RYGB to single anastomosis duodeno-ileal bypass with sleeve (SADI-S) or biliopancreatic diversion with duodenal switch (BPD-DS) due to weight regain between December 31, 2013 and October 31, 2018. For the body mass index (BMI) analysis, the multilevel model for change was used.

RESULTS: Of 15 patients, 10 underwent a conversion to SADI-S, and 5 underwent a conversion to BPD-DS. Also, 7 patients underwent the conversion in two-stages, while 8 did as single-stage. One patient had a duodenal stump leak after SADI-S, and another patient had a sleeve leak after BPD-DS. One patient underwent a reoperation to increase the common channel 20 months after the conversion to BPD-DS due to malnutrition. There was no mortality. Mean percentage of total weight loss (TWL) was 18.4% at 6 months, 25.0% at 12 months, 26.4% at 18 months, and 25.7% at 24 months after the conversion. The rate of decrease in BMI was slower in SADI-S patients than in BPD-DS patients (p < 0.01), adjusting for preoperative BMI.

CONCLUSION: Conversions of RYGB to SADI-S and BPD-DS can provide significant additional weight loss. However, complications and malnutrition can develop after the conversion, and further research is needed for evaluating safety.

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Conversions of Roux-en-Y gastric bypass to duodenal switch (SADI-S and BPD-DS) for weight regain

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