Cost-effectiveness of intermittent preventive treatment with dihydroartemisinin-piperaquine versus single screening and treatment for the control of malaria in pregnancy in Papua, Indonesia: a provider perspective analysis from a cluster-randomised trial

Nov 21, 2020The Lancet. Global health

Cost-effectiveness of preventive malaria treatment versus single screening during pregnancy in Papua, Indonesia from a healthcare provider perspective

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Abstract

Intermittent preventive treatment with dihydroartemisinin-piperaquine averted 107.4 disability-adjusted life-years (DALYs) per 1000 women at an incremental cost of $5657 compared to single screening and treatment.

  • The average cost-effectiveness ratio was $53 per DALY averted.
  • Intermittent preventive treatment is proposed as a promising alternative for reducing malaria in pregnancy.
  • The higher cost of intermittent preventive treatment was largely due to the need for monthly administration.
  • DALYs were calculated based on outcomes such as fetal loss, neonatal death, low birthweight, maternal anemia, and clinical malaria.
  • Cost estimates were derived from observational studies and health facility costing data.

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