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Abstract
Long COVID is characterized by persistent symptoms following SARS-CoV-2 infection.
- Long COVID may involve sustained immune dysregulation that persists beyond the initial infection.
- Cytokine-mediated inflammation and complement activation could play roles in the condition's pathogenesis.
- Endothelial dysfunction and thromboinflammation are associated with the symptoms of Long COVID.
- Viral antigen persistence may contribute to the ongoing immune response seen in affected individuals.
- Emerging biomarkers are being evaluated for their potential relevance in understanding Long COVID.
- Immunotherapeutic strategies are evolving in response to the identified mechanisms of hyperinflammation.
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