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Decreased sensitivity of the circadian system to light in current, but not remitted depression
Reduced response of the body’s internal clock to light in active depression but not in recovered depression
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Abstract
Patients currently experiencing a depressive episode showed significantly lower levels of melatonin suppression to light compared to remitted patients and controls.
- Lower melatonin suppression in depressed patients suggests altered sensitivity of the circadian system to light.
- Remitted patients and healthy controls exhibited similar levels of melatonin suppression.
- The findings indicate a potential link between reduced light sensitivity and circadian misalignment in depression.
- The study's small sample size limits the ability to establish causal relationships.
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