DELLA and RING Finger proteins reduce plant growth hormone responses by attaching to specific gene control sites in Arabidopsis

The boi quadruple mutant exhibited a higher seed germination frequency in the presence of paclobutrazol.

• DELLA proteins are known to repress gibberellin (GA) responses, but their interactions with other proteins are not fully understood.
• Single mutants of four DELLA-interacting RING domain proteins did not significantly affect GA responses.
• The boi quadruple mutant showed enhanced GA signaling, leading to earlier flowering and a faster transition from juvenile to adult phases.
• Overexpression of BOI led to reduced GA signaling phenotypes.
• The GAI protein requires BOIs to inhibit certain GA responses.
• BOI and DELLA proteins bind to the promoters of specific GA-responsive genes and repress their expression.

Simplified