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Abstract
High-fat diet (HFD) may elevate deoxycholic acid (DCA), which is associated with anxiety- and depression-like behaviors in mice.
- Intestinal DCA levels could be linked to changes in mood and anxiety.
- Behaviors resembling anxiety and depression may be influenced by alterations in gut-brain signaling due to HFD.
- Further understanding of the peripheral mechanisms involved in this relationship is needed.
Simplified
Gut-Brain Axis