Onset and Progression of Diabetic Eye Disease During Treatment with Semaglutide or Tirzepatide, Including a Review of a Specific Type of Optic Nerve Damage

This study aims to compare diabetic retinal disease onset or progression between established semaglutide or tirzepatide users and patients without documented exposure to either drug.

• Diabetic retinal disease onset or progression is evaluated in relation to the use of semaglutide or tirzepatide.
• Secondary objectives include making comparisons based on specific medications and assessing visual acuity.
• Nonarteritic anterior ischemic optic neuropathy (NAION) cases are evaluated separately in a descriptive manner.

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