Dickdarmmikrobiom und Depression

Nov 6, 2016Der Nervenarzt

Gut Microbiome and Major Depression: Understanding Our Hidden Inner Influence

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Abstract

Microbiome analysis has become sufficiently inexpensive and feasible to study the interactions between the gut and brain.

  • The microbiota-gut-brain-axis involves complex interactions between the brain and gut, potentially affecting health across generations.
  • Gnotobiotic animal models are increasingly utilized to target specific research questions related to this axis.
  • Preliminary findings suggest a link between gut microbiome characteristics and aspects of the hypothalamus-pituitary-adrenal axis.
  • Initial insights indicate a potential role for the microbiota-gut-brain-axis in depressive disorders.
  • Current therapeutic approaches using psychobiotics have not yet demonstrated significant value in clinical trials.

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Full Text

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