Diurnal transcriptome atlas of a primate across major neural and peripheral tissues

Up to 81.7% of protein-coding genes in the baboon exhibit daily rhythms in expression across 64 tissues sampled every 2 hours.

• Diurnal gene expression patterns contribute to the functional specialization of various tissues.
• A total of 22 brain regions were included in the analysis of rhythmic transcription.
• Rhythmic expression is observed in genes involved in essential cellular functions, with variations across different tissues.
• Peaks in gene expression occur predominantly at dawn and dusk, with a notable quiescent period during early night.
• The study reveals distinct differences in the temporal organization of gene expression between diurnal and nocturnal animals.

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