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Abstract
Epigenetic DNA methylation may offer insights into four complex chronic conditions that are often mismanaged.
- Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), long COVID (LC), fibromyalgia (FM), and hypermobile Ehlers-Danlos syndrome (hEDS) exhibit overlapping symptoms.
- There is potential for shared underlying biological mechanisms among these conditions.
- DNA methylation serves as a useful framework for studying these interconnected disorders.
- Current studies on DNA methylation in ME/CFS, LC, and FM suggest that an integrated approach may enhance understanding of their mechanisms.
- This approach could assist in better diagnostic stratification and potentially improve patient outcomes.
Simplified
Long Covid