Full text is available at the source.
Dopamine modifies the balance of rod and cone inputs to horizontal cells of the Xenopus retina
Dopamine changes how light signals from rods and cones combine in frog eye cells
AI simplified
Abstract
Dopamine (greater than or equal to 2 microM) increased cone input while suppressing rod input to horizontal cells in the Xenopus retina.
- Dopamine at 10 microM depolarized horizontal cells by about 9 mV.
- D2-dopamine antagonists spiperone and metoclopramide demonstrated opposite effects to dopamine.
- D1-dopamine antagonist SCH 23390 did not affect horizontal cell activity.
- Light-evoked responses of rods were not modified by any of the agents tested.
AI simplified