Down-regulation of activity and expression of three transport-related proteins in the gills of the euryhaline green crab, Carcinus maenas, in response to high salinity acclimation

Nov 2, 2010Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

Reduced activity and levels of three salt-transport proteins in green crab gills after adjustment to high salt water

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Abstract

A one-week low salinity acclimation resulted in a four-fold increase in branchial carbonic anhydrase activity.

  • Hemolymph osmolality adjusted to low salinity levels after one week of acclimation.
  • mRNA expression for two carbonic anhydrase isoforms increased significantly (CAc 100-fold, CAg 7-fold), along with an 8-fold increase for the Na/K-ATPase α-subunit.
  • Upon returning to high salinity, hemolymph osmolality reached acclimated levels within 6 hours, while mRNA levels returned to baseline within one week.
  • Carbonic anhydrase activity did not change initially in response to high salinity, but gradually declined back to baseline over four weeks.
  • The timing of physiological and gene expression changes indicates rapid whole-organism adaptations, while protein expression adjustments are slower.

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