Effect of switching from dulaglutide to tirzepatide on blood glucose and renal function

Oct 27, 2024Drug discoveries & therapeutics

Changes in blood sugar and kidney function after switching from dulaglutide to tirzepatide

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Abstract

The patient experienced a decrease in HbA1c after switching from dulaglutide to tirzepatide.

  • Switching from dulaglutide to tirzepatide resulted in a decrease in HbA1c levels.
  • An increase in estimated glomerular filtration rate (eGFR) was observed following the switch.
  • Blood urea nitrogen (BUN) levels decreased after transitioning to tirzepatide.
  • This case suggests that switching to tirzepatide may inhibit the progression of renal impairment.
  • The efficacy and safety of such a switch have not been previously evaluated in clinical studies.

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