Competing interests. SAR holds patents for (1) Prevention of circadian rhythm disruption by using optical filters and (2) Improving sleep performance in subject exposed to light at night; SAR owns equity in Melcort Inc.; has provided paid consulting services to Sultan & Knight Limited, Bambu Vault LLC, Lucidity Lighting Inc.; and has received honoraria as an invited speaker and travel funds from Starry Skies Lake Superior, University of Minnesota Medical School, PennWell Corp., and Seoul Semiconductor Co. Ltd. These interests were reviewed and managed by Brigham and Women’s Hospital and Partners HealthCare in accordance with their conflict of interest policies. BAK, LKG, TC, report no conflicts. JPH reports being a paid consultant by Lutron, Inc. and McCullough Hill LLC. LKB reports personal fees from Boston Children’s Hospital, University of Helsinki and the AAA Foundation. CAC reports grants and contracts to BWH from Dayzz Live Well, Delta Airlines, Jazz Pharma, Puget Sound Pilots, Regeneron Pharmaceuticals/Sanofi; is/was paid consultant/speaker for Inselspital Bern, Institute of Digital Media and Child Development, Klarman Family Foundation, M. Davis and Co, National Council for Mental Wellbeing, National Sleep Foundation, Physician’s Seal, SRS Foundation, State of Washington Board of Pilotage Commissioners, Tencent, Teva Pharma Australia, With Deep, and Vanda Pharmaceuticals, in which CAC holds an equity interest; received travel support from Aspen Brain Institute, Bloomage International Investment Group, Inc., Dr. Stanley Ho Medical Development Foundation, German National Academy of Sciences, Ludwig-Maximilians-Universität München, National Highway Transportation Safety Administration, National Safety Council, National Sleep Foundation, Salk Institute for Biological Studies/Fondation Ipsen, Society for Research on Biological Rhythms, Stanford Medical School Alumni Association, Tencent Holdings, Ltd, and Vanda Pharmaceuticals; receives research/education gifts through BWH from Arbor Pharmaceuticals, Avadel Pharmaceuticals, Bryte, Alexandra Drane, Cephalon, DR Capital Ltd, Eisai, Harmony Biosciences, Jazz Pharmaceuticals, Johnson & Johnson, Mary Ann & Stanley Snider via Combined Jewish Philanthropies, NeuroCare, Inc., Optum, Philips Respironics, Regeneron, Regional Home Care, ResMed, Resnick Foundation (The Wonderful Company), San Francisco Bar Pilots, Sanofi SA, Schneider, Simmons, Sleep Cycle AB. Sleep Number, Sysco, Teva Pharmaceuticals, Vanda Pharmaceuticals; is/was an expert witness in legal cases, including those involving Advanced Power Technologies, Aegis Chemical Solutions, Amtrak; Casper Sleep Inc, C&J Energy Services, Catapult Energy Services Group, Covenant Testing Technologies, Dallas Police Association, Enterprise Rent-A-Car, Espinal Trucking/Eagle Transport Group/Steel Warehouse Inc, FedEx, Greyhound, Pomerado Hospital/Palomar Health District, PAR Electrical Contractors, Product & Logistics Services LLC/Schlumberger Technology, Puckett EMS, Puget Sound Pilots, Union Pacific Railroad, UPS, and Vanda Pharmaceuticals; serves as the incumbent of an endowed professorship given to Harvard by Cephalon; and receives royalties from McGraw Hill and Philips Respironics for the Actiwatch-2 and Actiwatch Spectrum devices. CAC’s interests were reviewed and are managed by the Brigham and Women’s Hospital and Mass General Brigham in accordance with their conflict-of-interest policies. GCB has no conflicts of interest relative to the scientific content of this manuscript. In the spirit of open disclosure, however, he reports having issued patents (USPTO 7678140 B2; 10603507; 10213619 B2 and 8366755 B2) and pending patents (USPTO 16/831737 and 16/657927) related to the photoreceptor system for melatonin regulation. That intellectual property has been licensed by Litebook Company Ltd. He has been a paid consultant by Lutron, Inc. and McCullough Hill LLC. He currently serves on a Scientific Advisory Board for PhotoPharmics. In addition, The Thomas Jefferson University’s Light Research Program (LRP) has received equipment donations from industry partners including Toshiba Materials, BIOS, Robern, and PhotoPharmics Company. The Philadelphia section of the IES, BIOS, Robern and Toshiba have made gifts to the LRP for programmatic, research and educational uses. MASH has provided limited consulting to The MathWorks, Inc. SWL (2018–2021) has received consulting fees from the BHP Billiton, EyeJust Inc., Lighting Science Group corporation/HealthE, Noble Insights, Rec Room, Six Senses, Stantec and Team C Racing; and has current consulting contracts with Akili Interactive, Apex 2100 Ltd., Consumer Sleep Solutions, Headwaters Inc., Hintsa Performance AG, KBR Wyle Services, Light Cognitive, Mental Workout/Timeshifter, and View Inc. He has received honoraria and travel or accommodation expenses from Bloxhub, Emory University, Estée Lauder, Ineos, MIT, Roxbury Latin School, and University of Toronto, and travel or accommodation expenses (no honoraria) from IES, Mental Workout, Solemma, and Wiley; and royalties from Oxford University Press. He holds equity in iSleep pty. He has received an unrestricted equipment gift from F. Lux Software LLC, a fellowship gift from Stockgrand Ltd and holds an investigator-initiated grant from F. Lux Software LLC and a Clinical Research Support Agreement and Clinical Trial Agreement with Vanda Pharmaceuticals Inc. He is an unpaid Board Member of the Midwest Lighting Institute (non-profit). He was a Program Leader for the CRC for Alertness, Safety and Productivity, Australia, through an adjunct professor position at Monash University (2015–2019). He is part-time adjunct professor at the University of Surrey, UK. He holds a pending patent for a ‘Method and system for generating and providing notifications for a circadian shift protocol’ (US20190366032A1). He has served as a paid expert in legal proceedings related to light, sleep and health.
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