Early time‐restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis

Dec 15, 2022Obesity (Silver Spring, Md.)

Early daily time-restricted eating is linked to changes in weight, metabolism, mood, and sleep in people who stick to the plan

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Abstract

Participants adhering to early time-restricted eating (eTRE) ≥5 days per week experienced a 3.7 kg reduction in body weight.

eTRE is associated with a decrease in body fat by 2.8 kg and a reduction in heart rate by 7 beats per minute.
Improvements in insulin resistance and glucose levels were noted, with reductions of 2.80 and 9 mg/dL, respectively.
Participants reported enhanced mood, including reduced fatigue and anger, despite experiencing less sleep and longer time to fall asleep.

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OBJECTIVE: Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed.

METHODS: Ninety patients aged 25 to 75 years old with obesity were randomized to early TRE (eTRE; 8-hour eating window from 07:00 to 15:00) or a control schedule (≥12-hour window) for 14 weeks. A per-protocol analysis of weight loss, body composition, cardiometabolic health, and other end points was performed.

RESULTS: Participants who adhered to eTRE ≥5 d/wk every week had greater improvements in body weight (-3.7 ± 1.2 kg; p = 0.003), body fat (-2.8 ± 1.3 kg; p = 0.04), heart rate (-7 ± 3 beats/min; p = 0.02), insulin resistance (-2.80 ± 1.36; p = 0.047), and glucose (-9 ± 5 mg/dL; p = 0.047) relative to adherers in the control group. They also experienced greater improvements in mood, including fatigue and anger; however, they self-reported sleeping less and taking longer to fall asleep.

CONCLUSIONS: For those who can consistently adhere at least 5 d/wk, eTRE is a valuable approach for improving body weight, body fat, cardiometabolic health, and mood. Further research is needed to determine whether eTRE's effects of shortening sleep but reducing fatigue are healthful or not.

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Early time‐restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis

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