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Effectiveness of semaglutide versus liraglutide for treating post‐metabolic and bariatric surgery weight recurrence
Comparing semaglutide and liraglutide for managing weight return after metabolic and bariatric surgery
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Abstract
At 12 months, patients treated with semaglutide experienced a 12.92% mean weight loss compared to 8.77% with liraglutide.
- Semaglutide is associated with greater weight loss compared to liraglutide in adults with post-metabolic and bariatric surgery weight recurrence.
- The adjusted odds of achieving at least 10% weight loss are 2.34 times higher for semaglutide users than for liraglutide users.
- For achieving at least 15% weight loss, the odds are 2.55 times greater with semaglutide compared to liraglutide.
- Weight-loss effectiveness of semaglutide does not vary significantly across different subgroups, including age, sex, and type of bariatric surgery.
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Key numbers
-12.92%
Weight Loss Change
Mean percentage weight change at 12 months for semaglutide group.
2.34
Odds of ≥10% Weight Loss
Adjusted odds ratio for weight loss ≥10% in semaglutide vs. liraglutide.
2.55
Odds of ≥15% Weight Loss
Adjusted odds ratio for weight loss ≥15% in semaglutide vs. liraglutide.