The Journal of comparative neurology

Outgoing neural pathways from the body clock area in golden hamsters

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Updated

Abstract

Major terminal fields of SCN-derived vasopressin were detected in the medial preoptic nucleus and several hypothalamic regions.

  • Efferent projections from the suprachiasmatic nucleus (SCN) were identified using an anterograde tracer.
  • Vasopressin-containing projections from the SCN were found in the medial preoptic nucleus, anterior paraventricular nucleus of the thalamus, and medial parvicellular part of the paraventricular nucleus of the hypothalamus.
  • Vasoactive intestinal peptide projections were localized to the anterior and dorsal parvicellular divisions of the paraventricular nucleus and medial dorsomedial nucleus.
  • Gastrin-releasing peptide-containing fibers were restricted to specific areas including the subparaventricular area and medial dorsomedial nucleus.
  • Additional SCN projections were observed that did not correspond to the three investigated peptides, indicating potential other signaling pathways.
  • Contralateral innervation of the SCN was noted, but the neurotransmitter involved remains unidentified.

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