Plant physiology

Efficient genome editing in common wheat using CRISPR-Cas12a delivered to growing shoot tips

CRISPR Gene Editing Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated

Abstract

Essence

A shoot apical meristem delivery method enabled multiplex CRISPR-Cas12a genome editing in common wheat.

Evidence

This plant genome-editing experiment used biolistic delivery of intron-optimized LbCas12a and variants into common wheat shoot apical meristems.

Caveat

The abstract reports editing efficiency in a plant delivery system but gives no detailed rates, target loci, off-target assessment, or field performance outcomes.

Simplified

Full Text

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Funding

Competing interests

No financial or commercial competing interests reported.
PubMed

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