Efficient gene editors for precise, heritable changes to multiple soybean genes

The optimized GmPEplus and CMMPE systems enabled more efficient heritable and multiplex prime editing in soybean.

This plant genome-editing platform study engineered soybean prime editors and tested them in hairy roots and stable transgenic lines, reporting up to 81.3% editing efficiency, a 13.1-fold boost from an independent AtU6 cassette, and multiplex editing of 2-12 genes in hairy roots and up to 3 genes in stable lines.

The results are platform performance data in soybean experimental systems, not evidence of breeding gains, field performance, or trait-level agricultural outcomes.