BMJ case reports

Persistent nausea linked to peptide injections containing retatrutide as a new health risk

Updated

Abstract

A woman in her mid-20s developed symptoms after receiving 4 dose-escalated subcutaneous injections of an unverified product reported to contain retatrutide.

  • Persistent nausea, vomiting, and diarrhea occurred despite treatment with intravenous fluids and antiemetics.
  • No alternative medical causes were identified through blood tests, urinalysis, abdominal ultrasound, and MRI.
  • Symptoms began to improve 2 days after hospital admission and resolved within 1 week.
  • The Naranjo score of 7 suggests a probable link between the injections and her symptoms.
  • This case highlights the potential risks of unverified substances marketed in wellness settings, which may not be disclosed in standard medication histories.

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