Proceedings (Baylor University. Medical Center)

Hidden risk of normal-sugar diabetic ketoacidosis caused by GLP-1 drugs in type 2 diabetes

Updated

Abstract

A 59-year-old woman with type 2 diabetes developed euglycemic diabetic ketoacidosis (EDKA) after starting dulaglutide following the discontinuation of SGLT-2 inhibitors.

  • EDKA is a rare but serious complication associated with type 2 diabetes.
  • The patient experienced nausea, vomiting, abdominal pain, and a modestly elevated glucose level.
  • Laboratory tests confirmed the diagnosis of EDKA.
  • Treatment included intravenous insulin and fluids, leading to recovery.
  • Dulaglutide was stopped, and there was no recurrence of EDKA during follow-up.
  • This case suggests that GLP-1 receptor agonists may trigger EDKA in certain patients.

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Full Text

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Funding

Competing interests

The authors report no funding or conflicts of interest. The patient consented to publication of this case report.The authors report no funding or conflicts of interest. The patient consented to publication of this case report.
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