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The efficacy and safety of exenatide once weekly in patients with type 2 diabetes
How well and how safely once-weekly exenatide works for people with type 2 diabetes
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Abstract
Exenatide once weekly (QW) is an approved treatment for type 2 diabetes (T2D) but may be less effective than liraglutide and semaglutide.
- Exenatide QW has been shown to be a safe and effective option for managing T2D.
- Head-to-head trials indicate that exenatide QW is inferior to liraglutide and semaglutide regarding impacts on fasting plasma glucose, glycated hemoglobin A1c, and body weight.
- There is evidence suggesting that exenatide QW may also be less effective than liraglutide and semaglutide in reducing cardiovascular risk.
- Current risk-benefit assessments favor liraglutide and semaglutide as the preferred treatments for T2D, supported by a consensus report from diabetes associations.
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