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Exercise alleviates osteoporosis by regulating the secretion of the Senescent Associated Secretory Phenotype
Exercise helps reduce osteoporosis by controlling harmful substances released by aging cells
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Abstract
Exercise is recognized for its cost-effectiveness and safety in managing osteoporosis.
- The elderly population is increasingly affected by metabolic bone diseases, particularly osteoporosis.
- Pharmacological therapies for osteoporosis, while beneficial, can lead to adverse effects with prolonged use.
- Exercise may improve metabolic bone diseases by influencing the Senescent Associated Secretory Phenotype (SASP).
- The specific mechanisms by which exercise regulates SASP and its effects on osteoporosis are not fully understood.
- This review aims to clarify how exercise affects SASP to support osteoporosis management and inform targeted therapies.
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