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Exercising with low muscle glycogen content increases fat oxidation and decreases endogenous, but not exogenous carbohydrate oxidation
Exercising with low muscle sugar stores increases fat use and lowers the breakdown of body carbohydrates but not those from food
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Abstract
Initiating exercise with low muscle glycogen does not impair exogenous carbohydrate oxidation (0.84 ± 0.14 g/min) compared to adequate glycogen levels (0.87 ± 0.16 g/min).
- Endogenous carbohydrate oxidation was significantly lower in the low glycogen condition (0.75 ± 0.29 g/min) compared to the adequate condition (1.17 ± 0.29 g/min).
- Fat oxidation was higher during low glycogen exercise (0.55 ± 0.10 g/min) compared to adequate glycogen exercise (0.38 ± 0.13 g/min).
- Muscle pyruvate dehydrogenase activity was lower before and after exercise in the low glycogen condition.
- Transcriptional regulation of fat metabolism genes was higher in the low glycogen state compared to the adequate glycogen state.
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