How Variations in the FTO Gene Are Linked to Obesity and Metabolic Syndrome in Ethnic Mongolians

Individuals with the rs9939609 AT genotype have a 1.312 times higher risk of obesity compared to those with the TT genotype.

• Body mass, body mass index (BMI), waist circumference, hip circumference, and waist-hip ratio were significantly higher in the obesity group compared to controls.
• The frequencies of the TT genotype and T allele were higher in the obesity group than in the control group.
• No significant differences were observed in the frequencies of the three genotypes or allele frequencies of rs1421085 between the two groups.
• Individuals with the rs9939609 AA genotype had a 1.896 times higher risk of obesity compared to those with the TT genotype.
• The AT and AA genotypes of rs9939609 were associated with significantly higher body weight, BMI, waist circumference, hip circumference, and waist-hip ratio.

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