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Fecal microbiome predicts treatment response after the initiation of semaglutide or empagliflozin uptake
Gut bacteria predict treatment response after starting semaglutide or empagliflozin
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Abstract
Semaglutide and empagliflozin use is associated with changes in the gut microbiome after treatment initiation.
- No changes in microbial diversity were detected following treatment initiation.
- The baseline gut microbiome predicted changes in levels for users of both medications.
- The findings suggest that semaglutide and empagliflozin impact the gut microbial community during treatment.
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Key numbers
−11.37 mmol/mol (1.11%)
Decrease in for semaglutide
Change in after 3 months of treatment.
−13.88 mmol/mol (0.88%)
Decrease in for empagliflozin
Change in after 3 months of treatment.
20
20 subjects enrolled
Total number of participants in the study.