EBioMedicine

Genetic factors linked to differences in daily body clock balance using genome-wide and health data analyses

Updated

Abstract

The Circadian Imbalance Index (CII) is a 0-5 score assessing genetic susceptibility to circadian disruption.

  • CII incorporates factors such as evening chronotype, sleep duration, neuroticism, caffeine consumption, and vitamin D levels.
  • Understanding the genetics behind CII may reveal insights into individual differences in health related to circadian rhythms.
  • The study highlights the complexity of genetic influences on circadian disruption and its various health impacts.

Simplified

Full Text

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Funding

Competing interests

Declaration of interests MKR reports consulting fees from Eli Lilly and Company and modest stock ownership in GSK, outside the submitted work. S.R. reports institutional grants or contracts from Google/Proxima, consulting fees from Amgen Inc, unpaid board membership with the National Sleep Foundation and the Alliance of Sleep Apnoea Partners, and a stipend for an editor role at Sleep Health, all outside the submitted work. Other authors have no relevant financial or non-financial interests to disclose.
PubMed

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