Full text is available at the source.
Abstract
Understanding the sex-dependent relationship between polygenic risk for chronotypes, childhood traumas, and depression is critical.
- Depression is influenced by various neurobiological factors and can manifest in different forms.
- Distinct depressive phenotypes may be driven by early trauma and other biological factors.
- Sex differences could play a significant role in both the development and treatment of depression.
- Investigating polygenic risk for chronotypes may reveal insights into these sex-dependent associations.
Simplified