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Genetics of Circadian Rhythms
Genes that influence the body's internal clock
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Abstract
Nearly all organisms exhibit time-dependent behavior and physiology known as circadian rhythms.
- Circadian rhythms are influenced by a core transcription/translation feedback loop.
- Cyclic gene expression patterns regulate processes like metabolism, hormone activity, and nerve function.
- Daily inputs, such as light and food, help synchronize these cellular clocks.
- Disruption of the feedback loop may lead to various disorders and diseases.
- This has prompted increased interest in developing circadian-based therapies.
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