How Genes, Obesity, and Environment Relate to Type 2 Diabetes
Updated
Abstract
Obesity was considerably more frequent among diabetic subjects, with a significant association found between diabetes and consanguineous marriage.
- The mean age of diabetic patients was 45.5 years, compared to 42.4 years for controls.
- Statistically significant differences in body mass index, education level, consanguineous marriage, and number of children were observed between diabetic and control subjects.
- A family history of diabetes in first-degree relatives was reported in 62.1% of diabetic patients, compared to 44.4% of controls.
- Diabetes was found to be significantly more common in individuals from consanguineous marriages, with 33.1% of diabetic subjects affected versus 24.6% of controls.
- Higher systolic blood pressure and fasting glucose levels were significantly noted in diabetic patients compared to controls.
- Several risk factors for diabetes were identified, including smoking, consanguinity, body mass index, education level, number of children, and systolic blood pressure.
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