[Advances in genome editing and lodging resistance in sugarcane].

Jan 29, 2026Sheng wu gong cheng xue bao = Chinese journal of biotechnology

Improving sugarcane's resistance to falling over using new gene editing methods

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CRISPR Gene Editing on OpenScience ↗PubMed ↗DOI ↗

Abstract

Sugarcane contributes about 90% of sugar and 40% of bioethanol in China.

Conventional breeding methods face challenges due to the large genome and complex genetics of sugarcane.
Genome editing technologies, including CRISPR/Cas, have advanced the ability to modify specific genes efficiently.
The decoding of the sugarcane genome has opened new avenues for genetic improvement in this polyploid species.
There is potential for genome editing to create lodging-resistant sugarcane varieties.
This review discusses the status of genetic transformation and the application of genome editing in sugarcane breeding.

AI simplified

Sugarcane (spp.) is an important cash crop that provides about 90% of sugar and 40% of bioethanol in China. Due to its large genome and complicated genetic background, conventional breeding is difficult to achieve efficient genetic improvement of sugarcane. Genome editing is a disruptive technology in life sciences, enabling precise and efficient modification of target genes. From zinc-finger nucleases (ZFNs) to transcription activator-like effector nucleases (TALENs), the CRISPR/Cas system and the derived base editing and prime editing, these technologies have greatly advanced genetic research and upgraded biological breeding. With the decoding of the sugarcane genome, genome editing has provided a new technical means for the genetic improvement of polyploid sugarcane. This article provides a comprehensive review of the trajectory of genome editing in plants, the optimization of the CRISPR/Cas system, the genetic transformation status of sugarcane, the development of sugarcane genomics, and the application of genome editing in sugarcane. It focuses on exploring the application prospects of genome editing in breeding lodging-resistant sugarcane varieties. This review aims to provide valuable references for promoting the use of genome editing in sugarcane breeding. Saccharum

[Advances in genome editing and lodging resistance in sugarcane].

Abstract

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