Use of GLP-1 drugs linked to lower rates of bone fusion problems and swallowing difficulties after neck spine surgery, with effects changing over time

The study evaluates the association between GLP-1 receptor agonist use and complications following anterior cervical discectomy and fusion (ACDF).

• Complications such as pseudarthrosis, dysphagia, and the need for revision surgery are significant concerns after ACDF surgery.
• Patients with diabetes mellitus and obesity may face higher risks of these complications.
• GLP-1 receptor agonists have shown potential benefits in reducing inflammation and influencing bone health in orthopedic contexts.
• The relationship between GLP-1 RA use and cervical fusion outcomes is not well understood, particularly regarding the timing of therapy.
• This study aims to clarify the impact of GLP-1 RA use on various postoperative complications.

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