JAMA

Unapproved GLP-1 Drugs Retatrutide and Zenagamtide Sold Online May Not Be Safe or Effective

Updated

Abstract

The black market for two unapproved GLP-1 weight loss drugs is growing rapidly.

  • The demand for these drugs may stem from their perceived effectiveness in weight loss.
  • Unregulated access to these medications could pose significant health risks to users.
  • The absence of oversight may result in variations in drug quality and safety.
  • Potential side effects and long-term consequences of using these unapproved drugs remain unclear.

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