Annals of Indian Academy of Neurology

Early Treatment with GLP-1 Receptor Agonists in Acute Stroke and High-Risk Mini-Stroke: A Review of Randomized Trials

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Abstract

A systematic review and meta-analysis was conducted to evaluate the efficacy and safety of glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy after acute ischemic stroke or high-risk transient ischemic attack.

  • The role of GLP-1RA therapy in the early treatment of acute ischemic stroke or high-risk transient ischemic attack is currently uncertain.
  • Existing randomized evidence related to the use of GLP-1RA in this context was systematically reviewed.
  • Both efficacy and safety outcomes of GLP-1RA therapy in patients post-stroke were assessed.

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