Expert review of clinical immunology

GLP-1 receptor agonists may help brain diseases by changing immune cells and reducing brain inflammation

Updated

Abstract

Neuroinflammation is linked to the development and progression of various central nervous system diseases.

  • Effective treatments for central nervous system diseases are currently limited.
  • Glucagon-like peptide-1 receptor agonists (GLP-1RAs) may help reduce neuroinflammation.
  • Preclinical evidence indicates that GLP-1RAs could influence immune cell-related processes.
  • The therapeutic potential of GLP-1RAs in central nervous system diseases is suggested by this evidence.

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