Ophthalmic surgery, lasers & imaging retina

Using GLP-1 Receptor Medicines: Safety and Care for Patients Having Eye Surgery

Updated

Abstract

GLP-1 receptor agonists are associated with delayed gastric emptying, which raises concerns in the perioperative setting.

  • Delayed gastric emptying may increase the risk of aspiration during ophthalmic procedures.
  • The need for adjunctive sedation or conversion to deeper sedation could be necessary due to the effects of GLP-1 receptor agonists.
  • Preoperative screening and interdisciplinary coordination are emphasized as critical considerations when using GLP-1 receptor agonists in eye surgery.
  • Anesthesia guidelines are evolving in response to the implications of GLP-1 receptor agonist use.

Simplified

Funding

Competing interests

Disclosure: CRB is the Chief Medical Officer at Apellis. DVD has received contracts from Regeneron, Regenxbio, Ocular Therapeutix, Belite Bio, and Malinkrodt; is a consultant for Regeneron, Ocular Therapeutix, Regenxbio, Kodiak Sciences, Apellis, Astellas, Belite Bio, and Bayer; and holds stock or stock options in Kodiak Sciences. The remaining authors have disclosed no potential conflicts of interest, financial or otherwise.
PubMed

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