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Abstract
GLP-1 receptor agonist use was associated with a modest increase in overall infection risk compared to SGLT2 inhibitors.
- The overall infection risk was higher in patients using GLP-1 receptor agonists, with a hazard ratio of 1.04.
- Increased risks were specifically noted for biliary tract infections (HR 1.37), catheter-related infections (HR 1.34), and infective endocarditis (HR 1.31).
- No significant differences in infection risk were found for pneumonia, sepsis, or urinary tract infections.
- Subgroup analyses indicated consistent trends across various demographic factors like age, sex, BMI, and cardiovascular status.
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