North American Spine Society journal

Effects of GLP-1 receptor agonists on spine fusion success, safety, and risks in planned spine surgery

Updated

Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly used in patients with obesity and type 2 diabetes undergoing elective spine surgery.

  • GLP-1 RAs may improve metabolic risk profiles in patients with obesity and type 2 diabetes.
  • The associations of GLP-1 RAs with spinal fusion outcomes are not fully established.
  • Perioperative complications related to the use of GLP-1 RAs remain incompletely defined.
  • Procedure-specific outcomes for patients on GLP-1 RAs during elective spine surgery need further investigation.

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