Regional trends and disparities in newer GLP1 receptor agonist initiation among real‐world adult patients eligible for obesity treatment

Mar 4, 2025Diabetes, obesity & metabolism

Differences across regions in starting new GLP-1 medicines among adults eligible for obesity treatment

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Abstract

Only 1.8% of 319,949 adults initiated newer anti-obesity medications.

  • Semaglutide was the most commonly initiated medication, accounting for 77.9% of all initiations.
  • Liraglutide uptake peaked at 5% in 2018 but has since declined, while semaglutide and tirzepatide use has increased significantly since 2022.
  • Lower initiation odds were observed in Black and Hispanic populations compared to White individuals.
  • Medicaid and uninsured patients had lower initiation odds than those with private insurance.
  • Higher initiation odds were associated with being female, middle-aged, more outpatient visits, and consultations with endocrinologists.

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