Association of glucagon‐like peptide‐1 receptor agonist treatment with gastric residue in an esophagogastroduodenoscopy

Mar 15, 2023Journal of diabetes investigation

Link between glucagon-like peptide-1 receptor agonist treatment and leftover stomach contents during upper digestive tract exams

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Abstract

The proportion of gastric residue was statistically significantly higher in the GLP-1 receptor agonist treatment group at 5.4% compared to 0.49% in the non-treatment group (P = 0.004).

  • GLP-1 receptor agonist () treatment is associated with increased gastric residue as observed during .
  • The study included a matched pair case-control design with 1,128 individuals with diabetes, ultimately analyzing 205 matched pairs.
  • Statistical analysis was performed using the McNemar test to compare gastric residue presence between treatment and non-treatment groups.
  • Gastric residue was observed in 11 patients who received various GLP-1RA medications, including liraglutide, dulaglutide, and semaglutide.

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Key numbers

5.4%
Increase in Gastric Residue Proportion
Proportion of gastric residue in -treated patients
0.49%
Gastric Residue in Non-treated Patients
Proportion of gastric residue in patients not treated with
205 pairs
Matched Patient Pairs
Number of matched pairs analyzed for gastric residue

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