The Journal of the Association of Physicians of India

Practical Challenges and Factors Linked to Success in GLP-1 Receptor Agonist Treatment

Updated

Abstract

Real-world discontinuation rates of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in managing type 2 diabetes and obesity are higher than those reported in clinical trials.

  • GLP-1 receptor agonists have shown strong effectiveness in controlling blood sugar levels and aiding weight loss.
  • These medications also have potential cardiovascular benefits.
  • Discrepancies exist between the success rates observed in clinical trials and those seen in everyday clinical practice.
  • Higher discontinuation rates in real-world settings may indicate challenges in maintaining treatment adherence.

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