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The effect of glucagon‐like peptide‐1 receptor agonists on cardiac function and structure in patients with or without type 2 diabetes mellitus: An updated systematic review and meta‐analysis
Glucagon-like peptide-1 receptor agonists and their effects on heart function and structure in people with and without type 2 diabetes
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Abstract
GLP-1 receptor agonists improved the E/e' ratio by a mean difference of -0.73.
- GLP-1 receptor agonists significantly reduced left ventricular mass by a mean difference of -3.86 g.
- A reduction in left atrial volume of -8.20 mL was observed with GLP-1 receptor agonist treatment.
- NT-proBNP levels decreased by a standardized mean difference of -0.27, indicating improved cardiac stress.
- Patients showed an increase of 22.31 meters in the 6-minute walk test results, reflecting enhanced exercise capacity.
- No significant change in left ventricular ejection fraction was noted, with a mean difference of +0.31%.
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