Effects of glucagon-like peptide 1 receptor agonists on comorbidities in older patients with diabetes mellitus

Jul 20, 2019Therapeutic advances in chronic disease

Effects of glucagon-like peptide 1 drugs on other health problems in older adults with diabetes

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Abstract

Elderly patients with diabetes are at high risk of polypharmacy, which increases the likelihood of adverse drug events.

  • Polypharmacy is prevalent among elderly patients with diabetes due to multiple coexisting diseases and syndromes.
  • Cognitive and sensory deficits in these patients may hinder timely reporting of adverse drug events.
  • Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may help reduce the number of medications needed for managing diabetes and its comorbidities.
  • GLP-1 RAs have multiple effects on conditions commonly associated with diabetes, such as hyperlipidemia, hypertension, and fatty liver.
  • Using GLP-1 RAs could potentially lower costs, decrease medication burden, and improve adherence among older patients.

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