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Effect of the glucagon‐like peptide‐1 receptor agonists on diabetic peripheral neuropathy: A meta‐analysis
Glucagon-like peptide-1 receptor drugs and their effects on nerve damage in diabetes: A combined analysis
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Abstract
Following GLP-1RA treatment, nerve conduction velocity (NCV) improved significantly by 1.74 compared to the control group.
- The meta-analysis included six studies with a total of 271 participants.
- GLP-1RA treatment led to a significant increase in NCV (MD 1.74; 95% CI 1.16 to 2.33; p < 0.001).
- NCV also improved significantly when comparing measurements before and after treatment (MD 2.16; 95% CI 1.04 to 3.27; p < 0.001).
- No significant changes were observed in blood glucose levels (MD -0.20; 95% CI -0.87 to 0.46; p = 0.55), suggesting other mechanisms at play.
- The findings are preliminary due to the limited population studied, indicating a need for further research.
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