The American journal of medicine

Effects of Glucagon-Like Peptide-1 Receptor Agonists on Lung and Digestive Problems After Anesthesia in a Large International Study

Updated

Abstract

The use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may be associated with postoperative complications in patients undergoing general anesthesia.

  • GLP-1 RAs are known to delay gastric emptying.
  • Concerns have been raised regarding the risk of perioperative aspiration.
  • This target trial emulation evaluates the potential link between GLP-1 RA use and postoperative pulmonary and gastrointestinal adverse events.

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