Improvement of glycaemic control and treatment satisfaction by switching from liraglutide or dulaglutide to subcutaneous semaglutide in patients with type 2 diabetes: A multicentre, prospective, randomized, open‐label, parallel‐group comparison study (SWITCH‐SEMA 1 study)

Feb 1, 2023Diabetes, obesity & metabolism

Better blood sugar control and treatment satisfaction after switching from liraglutide or dulaglutide to injected semaglutide in type 2 diabetes patients

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Abstract

In a study of 110 patients, switching to once-weekly semaglutide significantly reduced glycated haemoglobin levels.

  • Patients switching from liraglutide showed a reduction in glycated haemoglobin from 7.9% to 7.3%.
  • Those switching from dulaglutide experienced a decrease in glycated haemoglobin from 7.8% to 7.1%.
  • Diabetes Treatment Satisfaction Questionnaire scores improved significantly in both groups after switching to semaglutide.
  • The increase in treatment satisfaction was +8.3 for the liraglutide group and +3.5 for the dulaglutide group.
  • Switching from dulaglutide resulted in greater reductions in body weight and better metabolic outcomes.

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