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Abstract
Individuals with autism spectrum disorder (ASD) frequently exhibit dysbiosis, characterized by an imbalance in gut microbial composition.
- Gut dysbiosis in ASD is associated with reduced microbial diversity and increased intestinal permeability.
- These microbial changes contribute to systemic inflammation, which may affect brain function.
- Alterations in gut microbiota could influence neurotransmitter synthesis and metabolic functions.
- Therapeutic approaches targeting the gut microbiome, such as probiotics and dietary modifications, have shown potential in alleviating gastrointestinal and ASD-related symptoms.
- Emerging evidence suggests that the gut-brain axis plays a crucial role in the pathophysiology of ASD.
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