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Abstract
Dysbiosis of the gut is related to a variety of neurodegenerative and neuropsychiatric diseases.
- The gut-brain axis involves complex communication between the gut and the central nervous system through various pathways.
- Gut microbiota may influence neurological health by regulating the synthesis of neurotransmitters.
- Emerging evidence suggests that imbalances in gut microbiota are associated with conditions such as Parkinson's disease, Alzheimer's disease, and depression.
- Gut microbes are linked to neuroimmune signaling and the integrity of the blood-brain barrier.
- Microbiota-targeted interventions, including probiotics and dietary changes, may help restore microbial balance and improve disease symptoms.
- Future research is needed to understand microbial mechanisms and to conduct large, randomized controlled trials for microbiota-based therapies.
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